Prevalence and Antimicrobial Resistance Patterns of Pseudomonas aeruginosa Isolated from Sputum samples of Patients with Lower Respiratory Tract Infections in Amassoma, Nigeria

Abdulrasheed, B. A., John, E.,Tolulope, A.(2020). Antimicrobial Susceptibility Patterns and Bacterial isolates in Septicemia Patients Attending FMC Yenagoa. International journal of Research and Scientific innovation,7(4),134-143. Ahmed, S.M., Jakribettu, R.P., Kottakutty, S., Arya, B., Shakir, V.P.A. (2012). An emerging multi-drug resistant pathogen in a tertiary care centre in North Kerala. Annals. Biol. Res., 3(6): 2794-99. Ali A, Alhomidi AM, Al-Henhena N. (2018).Prevalence of Pseudomonas aeruginosa (P. aeruginosa) and antimicrobial susceptibility patterns at a private hospital in Sana'a,Yemen. Universal Journal of Pharmaceutical Research, 3(4): 12-18. https://doi.org/10.22270/ujpr.v3i4.177 AL-Magrami, R. T.F., Al-Shamahy, H.A.(2018). Pseudomonas aeruginosa skin-nasopharyngeal Colonization in the in-patients: prevalence, risk factors and antibiotic resistance in tertiary hospitals in Sana'a city- Yemen. Universal Journal of Pharmaceutical Research, 3(6), 17-22. https://doi.org/10.22270/ujpr.v3i6.219 Arora, D., Jindal, N., Kumar, R., Romit. (2011). Emerging antibiotic resistance in Pseudomonas aeruginosa. Int. J. Pharm. Sci., 3(2): 82-4.) Bush, K., Bradford, P.A. (2020).Epidemiology of β-Lactamase-producing pathogens. Clin Microbiol Rev, 33(2):e00047-19. doi:10.1128/CMR.00047-19. Cheesbrough, M. (2006). District Laboratory practice in Tropical Countries Part 2.Cambridge University Press, Cambridge, 38-70. Clinical and Laboratory Standards Institute (CLSI). (2021). Performance standards for antimicrobial susceptibility testing (31st Ed.). Cunha B.A.The fluoroquinolones for urinary tract infections: A review.Adv Ther.1994, 11(6):277-96. Cunha, B. A.,(2011). Nitrofurantoin: Preferred Empirical Therapy for Community Acquired Lower respiratory Tract infections. Mayo Clin Proc, 86(12), 1243-1244.doi:10.4065/mcp.2011.0411. Gellatly, S. L., & Hancock, R. E. W. (2013). Pseudomonas aeruginosa: New insights into pathogenesis and host defenses. FEMS Microbiology Reviews, 37(3), 409-453. Gibson, R. L., Burns, J. L., & Ramsey, B. W. (2003). Pathophysiology and management of pulmonary infections in cystic fibrosis. American Journal of Respiratory and Critical Care Medicine, 168(8), 789-798. Grossman, T.H.(2016). Tetracycline antibiotics and resistance. Cold Spring Harb. Perspect. Med. 6(4), a025387 Indu Biswal, Balvinder Singh Arora, Dimple Kasana, Neetushree. 2014. Incidence of multidrug resistant Pseudomonas Aeruginosa isolated from Burn Patients and Environment of Teaching Institution. J. clin. Diag. Res, 8(5). Lee, J., & Zhang, L. (2015). The hierarchy quorum sensing network in Pseudomonas aeruginosa. Protein & Cell, 6(1), 26-41. Livermore, D. M. (2002). Multiple mechanisms of antimicrobial resistance in Pseudomonas aeruginosa: Our worst nightmare? Clinical Infectious Diseases, 34(5), 634-640. Karl, A., & Lain, L. L. (2021). Β-lactam Resistance in Pseudomonas aeruginosa: Current Status, Future Prospect. Pathogens, 10(12), 1638. Ndoutamia, G., Fissou, H.Y., Nadjilem, D & Gatsing, D.(2017).Perception, Knowledge and Use of Antiiotic among Communities in Chad. African journal of Pharmacy and pharmacology, 11,260-265 Nikaido,, H., (2009).Multidrug Resistance in Bacteria. Annu Rev Biochem, 78:119-146. doi:10,1146/annurev.biochem.78.082907.145923 Ramirez, M.S.,& Tolmasky, M.E.(2010). Aminoglycoside modifying enzymes. Drug Resis Upd,13(6), 151-171. https://doi.org/10.1016/j.drup.2010.08.003 22. Sadikot, R. T., Blackwell, T. S., Christman, J. W., & Prince, A. S. (2005). Pathogen-host interactions in Pseudomonas aeruginosa pneumonia. American Journal of Respiratory and Critical Care Medicine, 171(11), 1307-1314. Saroj, G., Suhani, M. S., & Jyoti. (2016). Isolation of Pseudomonas aeruginosa from various Clinical Isolates and it Antimicrobial Resistance Pattern in a Tertiary Care Hospital. Int. J. Curr. Microbiol. App. Sci. 5(3): 247-253. doi: http://dx.doi.org/10.20546/ijcmas.2016.503.030 Strateva, T., & Yordanov, V.(2009). Pseudomonas aeruginosa- a phenomenon of bacterial resistance. J Med Microb , 58(9),1133-1148. https://doi.org/10.1099/jmm.0.009142-0 23 Thompson, A.E., Anisimowicz, Y.,Miedema, B et al(2016). The influence of gender and other patient characteristics on health care seeking behavior: a QUALICOPC study. BMC Fam Pract, 17: 38. Thornton, J. P., Hawkey, P. M., & Livermore, D. M. (2004). Multidrug resistance in clinical isolates of Pseudomonas aeruginosa. Journal of Antimicrobial Chemotherapy, 53(6), 868-874. World Health Organization (WHO). (2017). Global priority list of antibiotic-resistant bacteria to guide research, discovery, and development of new antibiotics.

Didi Baraikio (2026). Prevalence and Antimicrobial Resistance Patterns of Pseudomonas aeruginosa Isolated from Sputum samples of Patients with Lower Respiratory Tract Infections in Amassoma, Nigeria. Greener Journal of Epidemiology and Public Health. DOI: https://doi.org/10.15580/gjeph.2026.1.022826030